The Geelong-bound lanes of the Bellarine Highway, Newcomb will be closed in sections nightly as resurfacing works are carried out between Tuesday 15 and Thursday 24 March.
All work will take place between 7pm and 5am, with signed detours and traffic controllers on site to help direct motorists.
The first stage of closures will be between Coppards Road and Wilsons Road from Tuesday 15 to Thursday 17 March, and again from Sunday 20 to Monday 21 March.
The next stage will result in closure between Wilsons Road and Boundary from Tuesday 22 March to Thursday 24 March.
During this time, motorists are advised to use Townsend Road or Portarlington Road.
Real-time traffic conditions are available at traffic.vicroads.vic.gov.au or via the VicTraffic mobile app. The latest public transport information and network status is available at ptv.vic.gov.au or in the PTV mobile app.