Does your dog have osteoarthritis? If so your dog may be eligible to participate in a free clinical trial run by U-Vet Werribee Animal Hospital, in association with Paradigm Biopharma, which could improve osteoarthritis treatment in both dogs and humans.
There is a high unmet medical need for therapies for osteoarthritis that improve pain and lameness and delay the disease’s progression. There are strong similarities between osteoarthritis in dogs and people. Consequently, any advance in treating osteoarthritis in dogs may be of interest to osteoarthritis treatment in humans.
Pentosan Polysulfate Sodium (PPS) has been used for over 20 years to help dogs suffering from osteoarthritis. Short term (1 to 3 months) results show that PPS reduces pain and lameness and improves joint health in dogs. Our study aims to assess if those positive effects are long-lasting in dogs using state-of-the-art equipment, such as Magnetic Resonance Imaging or MRI, to evaluate the impact inside the osteoarthritic joint and Canine Gait analysing using a pressure-sensitive walkway.
The study results will help establish objective research evidence that could be used to advance clinical development of PPS as a potential treatment for osteoarthritis in humans. An interim analysis is showing positive results, but we need more study participants to provide a larger number of animals.
Dogs must be over 7 years of age with clinical signs of osteoarthritis, desexed and weigh between 15 and 35 kg.
If you are interested in participating in this clinical trial, please contact Thierry Beths at Thierry.beths@unimelb.edu.au
